All-Natural Southern Comfort on Hilton Head
Annie O's serves fresh, all-natural Southern cuisine featuring grass-fed beef, pastured pork, free-range chicken, and wild sustainable seafood. Located on Hilton Head Island, we're your neighborhood spot for traditional Southern favorites made with ingredients just like Mother Nature intended. Experience true Southern hospitality where quality makes all the difference!
Why All Natural …
One of the best ways to feature the traditional dishes of the South is to start with the best quality products available to us. We proudly serve fresh, never frozen, Naked Grass-Fed Beef. We use only All-Natural Pastured Pork that is 100% free of added hormones or antibiotics. Our poultry is fresh, Free-Range Chicken and Cage-Free Eggs that are free of any added hormones or antibiotics. Our seafood is wild caught, domestic, sustainable seafood that is fresh off the boat. and never imported.
Order Online for Pickup or Delivery
Skip the line and order directly from our website! Choose pickup or delivery to enjoy Annie O's all-natural Southern cuisine at home. Quick, easy ordering puts our fresh, quality meals just a few clicks away. Order now and taste what real ingredients can do!
Fresh Ingredients, Beautiful Presentations
Discover our all-natural Southern cuisine through stunning food photography showcasing quality ingredients and traditional preparation.
Full-Service Catering for Every Occasion
Annie O's handles all your catering needs from small family gatherings to large corporate events. We offer everything from setup to cleanup, plus on-site and off-site options with personal chef services. Social luncheons, business events, birthday parties, holiday celebrations - if you need it, we provide it with our signature all-natural Southern cuisine!
Cozy Southern Hospitality Awaits Inside
Enjoy dining with Southern hospitality in our comfortable, intimate dining room. This hidden gem on Hilton Head Island provides a relaxed atmosphere for couples, friends, and families to gather. We welcome customers like family, offering counter service during lunch (11am-3pm) and full dine-in service evenings starting at 4pm. True Southern comfort!
Find Us on Target Road, Hilton Head Island
Visit Annie O's at 11 Target Rd, Hilton Head Island, SC 29928. We're open Sunday 12-7pm, Monday through Friday 11am-9pm, and Saturday 12-9pm. This local favorite serves fresh, all-natural Southern cuisine in a cozy atmosphere. Come taste the difference that quality ingredients make - we're ready to welcome you with true Southern hospitality! 📍
What our guests are saying
This is a "hidden gem" and now one of our favourite places on the Island. We had the soft shell crab basket and it was the best soft shell crab we've ever had! Jim, the owner, is a fantastic cook! We love this place.
Tammy M.
Really enjoyed the Lunch Plate option here. I had the chicken and French toast and the meatloaf. Friendly staff, quick service, and good parking.
Cora G.
What a great find tonight. The food was delicious and fresh. We had a variety of entrées, including the crab cakes, fried chicken, and pan-seared flounder. Service was very nice as well. We'll be back for sure.
Bob A.
Featuring
Delivery
Takeout
Catering
Dine In
Easy Parking
Vegetarian Options
Kids' Menu
Annie O's Rewards
Join our rewards program, earn points every time you order online, and redeem your points for free food!
Frequently Asked Questions
What are you known for?
We are known for Fruit Bowl, Pulled Pork, Chicken Salad, Lobster Roll, Blt, Fried Chicken Tenders, Dessert, BBQ, Buttermilk Biscuits, Southern Fried Chicken, Lobster, Fried Chicken Wings, Chicken, Oysters, Brisket, Tater Tots, Brunswick Stew, Crab, Cheeseburger, Key Lime Pie, Hot Dogs, Chicken Tenders, Nashville Hot Chicken, BBQ Brisket, Breakfast Sandwich, Meatloaf, Grilled Chicken, Prime Rib, Pimento Cheese, Oyster, French Toast, Deviled Eggs, Wings, Chicken Nuggets, Salads, Grilled Cheese, Baked Beans, Cheesecake, Fish, Chicken Sandwich, Collard Greens, Tomato Pie, Shrimp, Chicken Wings, Hot Chicken, Healthy Food, French Fries, Chicken Strips, Fried Chicken, Banana Pudding, Seafood, Biscuits, Fries, Grits, and Caesar Salad
Where are you located?
We are located in Hilton Head Island, SC at 11 Target Rd
What areas do you serve?
We serve the following areas: Hilton Head Island, Forest Beach, Spanish Wells, Hickory Bluff, Folly Field, Buckingham Landing, Brighton Beach, Daufuskie Island, Myrtle Island, Palmetto Bluff, Daufuskie Landing, Bluffton.
Our location
